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Unbiased Estimation of Linkage Disequilibrium from Unphased Data

Linkage disequilibrium (LD) is used to infer evolutionary history, to identify genomic regions under selection, and to dissect the relationship between genotype and phenotype. In each case, we require accurate estimates of LD statistics from sequencing data. Unphased data present a challenge because...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Biol Evol
Prif Awduron: Ragsdale, Aaron P, Gravel, Simon
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7038669/
https://ncbi.nlm.nih.gov/pubmed/31697386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msz265
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