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Unbiased Estimation of Linkage Disequilibrium from Unphased Data
Linkage disequilibrium (LD) is used to infer evolutionary history, to identify genomic regions under selection, and to dissect the relationship between genotype and phenotype. In each case, we require accurate estimates of LD statistics from sequencing data. Unphased data present a challenge because...
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| Publicat a: | Mol Biol Evol |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7038669/ https://ncbi.nlm.nih.gov/pubmed/31697386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msz265 |
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