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Downregulation of type I collagen expression in the Achilles tendon by dexamethasone: a controlled laboratory study

BACKGROUND: Spontaneous Achilles tendon rupture associated with long-term dexamethasone (Dex) use has been reported. However, few studies have investigated the potential mechanism. The aim of this study was to evaluate the effects of oral Dex on type I collagen in humans and rats and its association...

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Bibliographische Detailangaben
Veröffentlicht in:J Orthop Surg Res
Hauptverfasser: Ge, Zilu, Tang, Hong, Chen, Wan, Wang, Yunjiao, Yuan, Chengsong, Tao, Xu, Zhou, Binghua, Tang, Kanglai
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7038574/
https://ncbi.nlm.nih.gov/pubmed/32093733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13018-020-01602-z
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