Akt inhibitor deguelin aggravates inflammation and fibrosis in myocarditis

OBJECTIVE(S): Myocarditis is characterized by inflammatory cell infiltration in myocardial stroma. Attenuation of tumor necrosis factor (TNF)-α and interleukin (IL)-1β is a reliable mark for improving the prognosis. Protein kinase B (Akt) plays an important role in the development and progression of...

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Enregistré dans:
Détails bibliographiques
Publié dans:Iran J Basic Med Sci
Auteurs principaux: Li, Shanshan, Wang, Yue, Zhao, Chunming, Zhang, Meixiang, Wang, Wei, Yu, Xiaowei, Huang, Jiao, Wang, Zhao, Zhu, Bo, Yin, Chengqian, Cai, Hongxing
Format: Artigo
Langue:Inglês
Publié: Mashhad University of Medical Sciences 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7038425/
https://ncbi.nlm.nih.gov/pubmed/32128091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/ijbms.2019.35518.8473
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