Colon Targeting of Naringin for Enhanced Cytoprotection Against Indomethacin-Induced Colitis in Rabbits

BACKGROUND: Naringin is a promising anti-inflammatory drug against various disorders including ulcerative colitis. However, its oral bioavailability is low (8%) possibly due to cleavage at the upper gut. Consequently, colon targeting would be necessary for drug protection at the upper gut, enhanced...

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Dettagli Bibliografici
Pubblicato in:Drug Des Devel Ther
Autori principali: El Naggar, Eman Ebrahim, Mohamed, Elham Abdelmonem, Borg, Thanaa Mohamed, El-Sheakh, Ahmed Ramadan, Hamed, Mohammed Fawzy
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove 2020
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7038417/
https://ncbi.nlm.nih.gov/pubmed/32109993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S218357
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