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A Population Pharmacokinetics and Pharmacodynamic Approach To Optimize Tazobactam Activity in Critically Ill Patients

The percentage of the time that the free drug concentration remains above a concentration threshold (%fT > concentration threshold) has frequently been identified to be the optimal pharmacokinetic (PK)-pharmacodynamic (PD) target of interest for tazobactam using in vitro infection models. Similar...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Kalaria, Shamir N., Gopalakrishnan, Mathangi, Heil, Emily L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7038264/
https://ncbi.nlm.nih.gov/pubmed/31871076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02093-19
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