Hydroxylamine and Carboxymethoxylamine Can Inhibit Toxoplasma gondii Growth through an Aspartate Aminotransferase-Independent Pathway

Toxoplasma gondii is an obligate intracellular protozoan parasite and a successful parasitic pathogen in diverse organisms and host cell types. Hydroxylamine (HYD) and carboxymethoxylamine (CAR) have been reported as inhibitors of aspartate aminotransferases (AATs) and interfere with the proliferati...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Li, Jixu, Guo, Huanping, Galon, Eloiza May, Gao, Yang, Lee, Seung-Hun, Liu, Mingming, Li, Yongchang, Ji, Shengwei, Jia, Honglin, Xuan, Xuenan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7038254/
https://ncbi.nlm.nih.gov/pubmed/31907178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01889-19
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