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Phytocannabinoids in Neurological Diseases: Could They Restore a Physiological GABAergic Transmission?

γ-Aminobutyric acid type A receptors (GABA(A)Rs) are the main inhibitory mediators in the central nervous system (CNS). GABA(A)Rs are pentameric ligand gated ion channels, and the main subunit composition is usually 2α2βγ, with various isotypes assembled within a set of 19 different subunits. The in...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Cifelli, Pierangelo, Ruffolo, Gabriele, De Felice, Eleonora, Alfano, Veronica, van Vliet, Erwin Alexander, Aronica, Eleonora, Palma, Eleonora
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7038116/
https://ncbi.nlm.nih.gov/pubmed/31979108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21030723
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