Multifaceted Analyses of Epidermal Serine Protease Activity in Patients with Atopic Dermatitis

The serine proteases kallikrein-related peptidase (KLK) 5 and KLK7 cleave cell adhesion molecules in the epidermis. Aberrant epidermal serine protease activity is thought to play an important role in the pathogenesis of atopic dermatitis (AD). We collected the stratum corneum (SC) from healthy indiv...

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Publié dans:Int J Mol Sci
Auteurs principaux: Nomura, Hayato, Suganuma, Mutsumi, Takeichi, Takuya, Kono, Michihiro, Isokane, Yuki, Sunagawa, Ko, Kobashi, Mina, Sugihara, Satoru, Kajita, Ai, Miyake, Tomoko, Hirai, Yoji, Yamasaki, Osamu, Akiyama, Masashi, Morizane, Shin
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7038095/
https://ncbi.nlm.nih.gov/pubmed/32019242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21030913
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