Downregulation of Hypoxia-Inducible Factor-1α by RNA Interference Alleviates the Development of Collagen-Induced Arthritis in Rats

Rheumatoid arthritis (RA) is the most common type of autoimmune arthritis. Hypoxia-inducible factor-1α (HIF-1α) as a transcription factor in response to hypoxia suggests that it could be a potential therapeutic target for the treatment of RA. In this study, we assessed whether the HIF pathway blocka...

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Publicado en:Mol Ther Nucleic Acids
Main Authors: Hu, Yiping, Zhang, Tiantian, Chen, Jingqin, Cheng, WenXiang, Chen, Jianhai, Zheng, Zhengtan, Lin, Jietao, Zhu, Guoyuan, Zhang, Yong, Bai, Xueling, Wang, Yan, Song, Bing, Wang, Qingwen, Qin, Ling, Zhang, Peng
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Gene & Cell Therapy 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7038004/
https://ncbi.nlm.nih.gov/pubmed/32160704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.01.014
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