Deficiency in Dipeptidyl Peptidase-4 Promotes Chemoresistance Through the CXCL12/CXCR4/mTOR/TGFβ Signaling Pathway in Breast Cancer Cells

Dipeptidyl peptidase (DPP)-4, a molecular target of DPP-4 inhibitors, which are type 2 diabetes drugs, is expressed in a variety of cell types, tissues and organs. DPP-4 has been shown to be involved in cancer biology, and we have recently shown that a DPP-4 inhibitor promoted the epithelial mesench...

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Udgivet i:Int J Mol Sci
Main Authors: Li, Shaolan, Fan, Yang, Kumagai, Asako, Kawakita, Emi, Kitada, Munehiro, Kanasaki, Keizo, Koya, Daisuke
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7037814/
https://ncbi.nlm.nih.gov/pubmed/31991851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21030805
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