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Bumetanide Suppression of Angiogenesis in a Rat Model of Oxygen-Induced Retinopathy
Aquaporins (AQPs) are involved in hypoxia-induced angiogenesis and retinal damage. Bumetanide is a diuretic agent, Na(+)/K(+)/Cl(−) cotransporter (NKCC1), and AQP 1–4 inhibitor. We tested the hypothesis that early postnatal treatment with bumetanide suppresses biomarkers of angiogenesis and decrease...
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| Publicado no: | Int J Mol Sci |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7037744/ https://ncbi.nlm.nih.gov/pubmed/32024231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21030987 |
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