Impact of Janus Kinase Inhibition with Tofacitinib on Fundamental Processes of Bone Healing

Both inflammatory diseases like rheumatoid arthritis (RA) and anti-inflammatory treatment of RA with glucocorticoids (GCs) or non-steroidal anti-inflammatory drugs (NSAIDs) negatively influence bone metabolism and fracture healing. Janus kinase (JAK) inhibition with tofacitinib has been demonstrated...

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Udgivet i:Int J Mol Sci
Main Authors: Gaber, Timo, Brinkman, Antonia Clara Katharina, Pienczikowski, Justyna, Diesing, Karoline, Damerau, Alexandra, Pfeiffenberger, Moritz, Lang, Annemarie, Ohrndorf, Sarah, Burmester, Gerd-Rüdiger, Buttgereit, Frank, Hoff, Paula
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7037633/
https://ncbi.nlm.nih.gov/pubmed/32013232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21030865
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