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New Potent 5α- Reductase and Aromatase Inhibitors Derived from 1,2,3-Triazole Derivative

This work describes the utility of pyrazole-4-carbaldehyde 1 as starting material for the synthesis of a novel potent series of 5α-reductase and aromatase inhibitors derived from 1,2,3-triazole derivative. Condensation of 1 with active methylene and different amino pyrazoles produced the respective...

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Publicat a:Molecules
Autors principals: El-Naggar, Mohamed, Abd El-All, Amira S., El-Naem, Shweekar I. A., Abdalla, Mohamed M., Rashdan, Huda R. M.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7037409/
https://ncbi.nlm.nih.gov/pubmed/32033281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25030672
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