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Deep Eutectic Solvents as Effective Reaction Media for the Synthesis of 2-Hydroxyphenylbenzimidazole-Based Scaffolds en Route to Donepezil-Like Compounds

An unsubstituted 2-hydroxyphenylbenzimidazole has recently been included as a scaffold in a series of hybrids (including the hit compound PZ1) based on the framework of the acetylcholinesterase (AChE) inhibitor Donepezil, which is a new promising multi-target ligand in Alzheimer’s disease (AD) treat...

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Vydáno v:Molecules
Hlavní autoři: Piemontese, Luca, Sergio, Roberta, Rinaldo, Federica, Brunetti, Leonardo, Perna, Filippo M., Santos, M. Amélia, Capriati, Vito
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7037276/
https://ncbi.nlm.nih.gov/pubmed/32013037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25030574
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