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Human-Induced Neurons from Presenilin 1 Mutant Patients Model Aspects of Alzheimer’s Disease Pathology

Traditional approaches to studying Alzheimer’s disease (AD) using mouse models and cell lines have advanced our understanding of AD pathogenesis. However, with the growing divide between model systems and clinical therapeutic outcomes, the limitations of these approaches are increasingly apparent. T...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Schrank, Sean, McDaid, John, Briggs, Clark A., Mustaly-Kalimi, Sarah, Brinks, Deanna, Houcek, Aiden, Singer, Oded, Bottero, Virginie, Marr, Robert A., Stutzmann, Grace E.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7037274/
https://ncbi.nlm.nih.gov/pubmed/32033164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21031030
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