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Inflammasome signaling and regulation of interleukin-1 family cytokines
Specific IL-1 family cytokines are expressed by cells as cytosolic pro-forms that require cleavage for their activity and cellular release. IL-1β, IL-18, and IL-37 maturation and secretion is governed by inflammatory caspases within signaling platforms called inflammasomes. By inducing pyroptosis, i...
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| 發表在: | J Exp Med |
|---|---|
| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Rockefeller University Press
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7037238/ https://ncbi.nlm.nih.gov/pubmed/31611248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190314 |
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