Local and Systemic Humoral Response to Autologous Lineage-Negative Cells Intrathecal Administration in ALS Patients

Amyotrophic lateral sclerosis (ALS) remains a fatal disease with limited therapeutic options. Signaling via neurotrophins (NTs), neuroinflammation, and certain micro-RNAs are believed to play essential role in ALS pathogenesis. Lineage-negative stem/progenitor cells (Lin(−)) were obtained from bone...

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Publicado no:Int J Mol Sci
Main Authors: Baumert, Bartłomiej, Sobuś, Anna, Gołąb-Janowska, Monika, Ulańczyk, Zofia, Paczkowska, Edyta, Łuczkowska, Karolina, Zawiślak, Alicja, Milczarek, Sławomir, Osękowska, Bogumiła, Meller, Agnieszka, Machowska-Sempruch, Karolina, Wełnicka, Agnieszka, Safranow, Krzysztof, Nowacki, Przemysław, Machaliński, Bogusław
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7037134/
https://ncbi.nlm.nih.gov/pubmed/32041109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21031070
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