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Synthesis of New Cisplatin Derivatives from Bile Acids

A series of bile acid derived 1,2- and 1,3-diamines as well as their platinum(II) complexes were designed and synthesized in hope to get a highly cytotoxic compound by the combination of two bioactive moieties. All complexes obtained were subjected to cytotoxicity assays in vitro and some hybrid mol...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Molecules
Main Authors: Seroka, Barbara, Łotowski, Zenon, Hryniewicka, Agnieszka, Rárová, Lucie, R. Sicinski, Rafal, M. Tomkiel, Aneta, W. Morzycki, Jacek
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI 2020
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7036801/
https://ncbi.nlm.nih.gov/pubmed/32033039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25030655
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