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Lipidated Analogs of the LL-37-Derived Peptide Fragment KR12—Structural Analysis, Surface-Active Properties and Antimicrobial Activity

An increasing number of multidrug-resistant pathogens is a serious problem of modern medicine and new antibiotics are highly demanded. In this study, different n-alkyl acids (C(2)-C(14)) and aromatic acids (benzoic and trans-cinnamic) were conjugated to the N-terminus of KR12 amide. The effect of th...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Kamysz, Elżbieta, Sikorska, Emilia, Jaśkiewicz, Maciej, Bauer, Marta, Neubauer, Damian, Bartoszewska, Sylwia, Barańska-Rybak, Wioletta, Kamysz, Wojciech
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7036753/
https://ncbi.nlm.nih.gov/pubmed/32019109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21030887
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