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Ca(2+)-Dependent Inactivation of GluN2A and GluN2B NMDA Receptors Occurs by a Common Kinetic Mechanism

N-Methyl-d-aspartate (NMDA) receptors are Ca(2+)-permeable channels gated by glutamate and glycine that are essential for central excitatory transmission. Ca(2+)-dependent inactivation (CDI) is a regulatory feedback mechanism that reduces GluN2A-type NMDA receptor responses in an activity-dependent...

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Bibliografske podrobnosti
izdano v:Biophys J
Main Authors: Iacobucci, Gary J., Popescu, Gabriela K.
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7036730/
https://ncbi.nlm.nih.gov/pubmed/31629478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.07.057
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