Biased visibility in Hi-C datasets marks dynamically regulated condensed and decondensed chromatin states genome-wide

BACKGROUND: Proximity ligation based techniques, like Hi-C, involve restriction digestion followed by ligation of formaldehyde cross-linked chromatin. Distinct chromatin states can impact the restriction digestion, and hence the visibility in the contact maps, of engaged loci. Yet, the extent and th...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Chandradoss, Keerthivasan Raanin, Guthikonda, Prashanth Kumar, Kethavath, Srinivas, Dass, Monika, Singh, Harpreet, Nayak, Rakhee, Kurukuti, Sreenivasulu, Sandhu, Kuljeet Singh
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7036197/
https://ncbi.nlm.nih.gov/pubmed/32087673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-020-6580-6
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