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Cyanomethylation of Substituted Fluorenes and Oxindoles with Alkyl Nitriles

The first example of metal-free cyanomethylenation from alkyl nitriles of sp(3) C-H bonds to afford quaternary carbon centers is described. This oxidative protocol is operationally simple and features good functional group compatibility. This method provides a novel approach to highly functionalized...

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Bibliografiske detaljer
Udgivet i:Org Lett
Main Authors: Hong, Gang, Nahide, Pradip D., Kozlowski, Marisa C.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7036039/
https://ncbi.nlm.nih.gov/pubmed/32043885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.0c00160
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