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A DNA-based fluorescent reporter maps HOCl production in the maturing phagosome
Phagocytes destroy pathogens by trapping them in a transient organelle called the phagosome where they are bombarded with reactive oxygen (ROS) and reactive nitrogen species (RNS). Imaging reactive species within the phagosome would directly reveal the chemical dynamics underlying pathogen destructi...
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| Pubblicato in: | Nat Chem Biol |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7034416/ https://ncbi.nlm.nih.gov/pubmed/30531966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-018-0176-3 |
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