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AMC-063: Safety and Efficacy of Bortezomib in AIDS-associated Kaposi Sarcoma

PURPOSE: AIDS-related Kaposi sarcoma (KS) is often incompletely controlled, requiring serial therapies. KS herpesvirus (KSHV) induces transformation of endothelial cells, where it resides in a predominately latent state. We hypothesized proteasome inhibition would have direct anti-tumor activity, in...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Reid, Erin G., Suazo, Adrienne, Lensing, Shelly, Dittmer, Dirk P., Ambinder, Richard F., Maldarelli, Frank, Gorelick, Robert J., Aboulafia, David, Mitsuyasu, Ronald, Dickson, Mark A., Wachsman, William
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7034393/
https://ncbi.nlm.nih.gov/pubmed/31624104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-1044
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