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Vibrio pore-forming leukocidin activates pyroptotic cell death via the NLRP3 inflammasome

Cell death mechanisms are central to combat infections and to drive inflammation. The inflammasome controls infection through activation of caspase-1 leading to either IL-1β dependent inflammation, or pyroptotic cell death in infected cells. Hemolysins, which are pore-forming toxins (PFTs), alter th...

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Dades bibliogràfiques
Publicat a:Emerg Microbes Infect
Autors principals: Cohen, Hadar, Baram, Noam, Edry-Botzer, Liat, Munitz, Ariel, Salomon, Dor, Gerlic, Motti
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7034064/
https://ncbi.nlm.nih.gov/pubmed/32013758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/22221751.2020.1720526
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