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Complex Stability and an Irrevertible Transition Reverted by Peptide and Fibroblasts in a Dynamic Model of Innate Immunity

We here apply a control analysis and various types of stability analysis to an in silico model of innate immunity that addresses the management of inflammation by a therapeutic peptide. Motivation is the observation, both in silico and in experiments, that this therapy is not robust. Our modeling re...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Abudukelimu, Abulikemu, Barberis, Matteo, Redegeld, Frank, Sahin, Nilgun, Sharma, Raju P., Westerhoff, Hans V.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7033641/
https://ncbi.nlm.nih.gov/pubmed/32117197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.03091
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