Comparative pharmacokinetic and tolerability evaluation of two simvastatin 20 mg formulations in healthy Korean male volunteers

Simvastatin is used to reduce plasma cholesterol by inhibiting 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase and is primarily used to treat hypercholesterolemia. This study was conducted to assess the bioequivalence between the generic formulation of simvastatin 20 mg and the branded for...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Transl Clin Pharmacol
Hauptverfasser: Moon, Seol Ju, Lee, SeungHwan, Jang, Kyungho, Yu, Kyung-Sang, Yim, Sung-Vin, Kim, Bo-Hyung
Format: Artigo
Sprache:Inglês
Veröffentlicht: Korean Society for Clinical Pharmacology and Therapeutics 2017
Schlagworte:
BE Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7033535/
https://ncbi.nlm.nih.gov/pubmed/32095453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12793/tcp.2017.25.1.10
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