Nitrite elicits divergent NO-dependent signaling that associates with outcome in out of hospital cardiac arrest

Brain and heart injury cause most out-of-hospital cardiac arrest deaths but limited pharmacotherapy exists to protect these tissues. Nitrite is a nitric oxide precursor that is protective in pre-clinical models of ischemic injury and safe in Phase I testing. Protection may occur by cGMP generation v...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Vitturi, Dario A., Maynard, Charles, Olsufka, Michele, Straub, Adam C., Krehel, Nick, Kudenchuk, Peter J., Nichol, Graham, Sayre, Michael, Kim, Francis, Dezfulian, Cameron
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7033352/
https://ncbi.nlm.nih.gov/pubmed/32087553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101463
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