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Methylenetetrahydrofolate reductase C677T (Ala>Val, rs1801133 C>T) polymorphism decreases the susceptibility of hepatocellular carcinoma: a meta-analysis involving 12,628 subjects

C677T (Ala>Val, rs1801133 C>T), a non-synonymous variant of methylenetetrahydrofolate reductase (MTHFR) gene, has been found to be associated with an impair enzyme activity of MTHFR. The relationship of MTHFR rs1801133 with hepatocellular carcinoma (HCC) has been extensively investigated. Howe...

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Detalhes bibliográficos
Publicado no:Biosci Rep
Main Authors: Zhang, Sheng, Jiang, Jiakai, Tang, Weifeng, Liu, Longgen
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7033308/
https://ncbi.nlm.nih.gov/pubmed/32010931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20194229
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