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H-Ferritin is essential for macrophages’ capacity to store or detoxify exogenously added iron

Macrophages are central cells both in the immune response and in iron homeostasis. Iron is both essential and potentially toxic. Therefore, iron acquisition, transport, storage, and release are tightly regulated, by several important proteins. Cytosolic ferritin is an iron storage protein composed o...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mesquita, Gonçalo, Silva, Tânia, Gomes, Ana C., Oliveira, Pedro F., Alves, Marco G., Fernandes, Rui, Almeida, Agostinho A., Moreira, Ana C., Gomes, Maria Salomé
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7033252/
https://ncbi.nlm.nih.gov/pubmed/32080266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-59898-0
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