Combined HER3-EGFR score in triple-negative breast cancer provides prognostic and predictive significance superior to individual biomarkers

Epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 3 (HER3) have been investigated as triple-negative breast cancer (TNBC) biomarkers. Reduced EGFR levels can be compensated by increases in HER3; thus, assaying EGFR and HER3 together may improve prognostic value. In a...

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Publicat a:Sci Rep
Autors principals: Ogden, Angela, Bhattarai, Shristi, Sahoo, Bikram, Mongan, Nigel P., Alsaleem, Mansour, Green, Andrew R., Aleskandarany, Mohammed, Ellis, Ian O., Pattni, Sonal, Li, Xiaoxian (Bill), Moreno, Carlos S., Krishnamurti, Uma, Janssen, Emiel A., Jonsdottir, Kristin, Rakha, Emad, Rida, Padmashree, Aneja, Ritu
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7033213/
https://ncbi.nlm.nih.gov/pubmed/32080212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-59514-1
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