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Genome of Tripterygium wilfordii and identification of cytochrome P450 involved in triptolide biosynthesis

Triptolide is a trace natural product of Tripterygium wilfordii. It has antitumor activities, particularly against pancreatic cancer cells. Identification of genes and elucidation of the biosynthetic pathway leading to triptolide are the prerequisite for heterologous bioproduction. Here, we report a...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Tu, Lichan, Su, Ping, Zhang, Zhongren, Gao, Linhui, Wang, Jiadian, Hu, Tianyuan, Zhou, Jiawei, Zhang, Yifeng, Zhao, Yujun, Liu, Yuan, Song, Yadi, Tong, Yuru, Lu, Yun, Yang, Jian, Xu, Cao, Jia, Meirong, Peters, Reuben J., Huang, Luqi, Gao, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7033203/
https://ncbi.nlm.nih.gov/pubmed/32080175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14776-1
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