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Relaxed sequence constraints favor mutational freedom in idiosyncratic metazoan mitochondrial tRNAs

Metazoan complexity and life-style depend on the bioenergetic potential of mitochondria. However, higher aerobic activity and genetic drift impose strong mutation pressure and risk of irreversible fitness decline in mitochondrial (mt)DNA-encoded genes. Bilaterian mitochondria-encoded tRNA genes, key...

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Dades bibliogràfiques
Publicat a:Nat Commun
Autors principals: Kuhle, Bernhard, Chihade, Joseph, Schimmel, Paul
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7033119/
https://ncbi.nlm.nih.gov/pubmed/32080176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14725-y
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