Protease Amplification of the Inflammatory Response Induced by Commensal Bacteria: Implications for Racial Disparity in Term and Preterm Birth

Decidual macrophages secrete proteases that activate protease-activated receptor 1 (PAR-1). We hypothesized that activation of the inflammatory response by bacteria is amplified by proteases, initiating labor. In addition, we hypothesized that commensal bacteria trigger an inflammatory response by a...

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Publicat a:Reprod Sci
Autors principals: Walsh, Scott W., Nugent, William H., Alam, S.M. Khorshed, Washington, Sonya L., Teves, Maria, Jefferson, Kimberly K., Strauss, Jerome F.
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2020
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7033026/
https://ncbi.nlm.nih.gov/pubmed/32046375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s43032-019-00011-w
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