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Antibody opsonization of a TLR9-agonist-containing virus-like particle enhances in situ immunization

The immunologic and therapeutic effects of intratumoral (IT) delivery of a novel virus-like particle (VLP) as a lymphoma immunotherapy were evaluated in preclinical studies with human cells and a murine model. CMP-001 is a VLP composed of the Qβ bacteriophage capsid protein encapsulating an immunost...

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Dades bibliogràfiques
Publicat a:J Immunol
Autors principals: Lemke-Miltner, Caitlin D., Blackwell, Sue E., Yin, Chaobo, Krug, Anna E., Morris, Aaron J., Krieg, Arthur M., Weiner, George J.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7033003/
https://ncbi.nlm.nih.gov/pubmed/31953355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900742
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