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Hyperglycemia-induced Ubiquitination and Degradation of β-catenin with the Loss of Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1) in Retinal Endothelial Cells

OBJECTIVE: Increased retinal vascular permeability is one of the earliest manifestations of diabetic retinopathy. The aim of this study was to investigate the role of hyperglycemia-induced platelet endothelial cell adhesion molecule −1 (PECAM-1) loss on retinal vascular permeability via the β-cateni...

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Bibliographic Details
Published in:Microcirculation
Main Authors: Eshaq, Randa S., Harris, Norman R.
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7032995/
https://ncbi.nlm.nih.gov/pubmed/31628816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/micc.12596
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