Formulation of a film-coated dutasteride tablet bioequivalent to a soft gelatin capsule (Avodart(®)): Effect of γ-cyclodextrin and solubilizers

The aim of this study was to optimize a tablet formulation of dutasteride that is bioequivalent to a commercially available soft gelatin capsule (Avodart(®)). The effect of cyclodextrin on enhancing the aqueous solubility of dutasteride was investigated, after which the formulation was further optim...

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Bibliografiske detaljer
Udgivet i:Asian J Pharm Sci
Main Authors: Min, Mi-Hong, Park, Jin-Hyong, Choi, Mi-Ran, Hur, Jong-Hyun, Ahn, Byung-Nak, Kim, Dae-Duk
Format: Artigo
Sprog:Inglês
Udgivet: Shenyang Pharmaceutical University 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7032202/
https://ncbi.nlm.nih.gov/pubmed/32104461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajps.2018.08.007
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