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Design and evaluation of an extended-release matrix tablet formulation; the combination of hypromellose acetate succinate and hydroxypropylcellulose

The purpose of this study was to develop an extended-release (ER) matrix tablet that shows robust dissolution properties able to account for the variability of pH and mechanical stress in the GI tract using a combination of enteric polymer and hydrophilic polymer. Hypromellose acetate succinate (HPM...

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Detalhes bibliográficos
Publicado no:Asian J Pharm Sci
Main Authors: Fukui, Sachiko, Yano, Hideki, Yada, Shuichi, Mikkaichi, Tsuyoshi, Minami, Hidemi
Formato: Artigo
Idioma:Inglês
Publicado em: Shenyang Pharmaceutical University 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7032166/
https://ncbi.nlm.nih.gov/pubmed/32104324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajps.2016.11.002
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