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Effects of granulation process variables on the physical properties of dosage forms by combination of experimental design and principal component analysis

The current study was to understand how process variables of high shear wet granulations affect physical properties of granules and tablets. The knowledge gained was intended to be used for Quality-by-Design based process design and optimization. The variables were selected based on the risk assessm...

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Detalhes bibliográficos
Publicado no:Asian J Pharm Sci
Main Authors: Thapa, Prakash, Choi, Du Hyung, Kim, Min Soo, Jeong, Seong Hoon
Formato: Artigo
Idioma:Inglês
Publicado em: Shenyang Pharmaceutical University 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7032112/
https://ncbi.nlm.nih.gov/pubmed/32104459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajps.2018.08.006
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