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Carboxylesterase 1 and Precision Pharmacotherapy: Pharmacogenetics and Nongenetic Regulators
Carboxylesterase (CES) 1 is the most abundant drug-metabolizing enzyme in human livers, comprising approximately 1% of the entire liver proteome. CES1 is responsible for 80%–95% of total hydrolytic activity in the liver and plays a crucial role in the metabolism of a wide range of drugs (especially...
में बचाया:
| में प्रकाशित: | Drug Metab Dispos |
|---|---|
| मुख्य लेखकों: | , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
The American Society for Pharmacology and Experimental Therapeutics
2020
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7031766/ https://ncbi.nlm.nih.gov/pubmed/31871135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.119.089680 |
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