Direct electrophysiological evidence that spreading depolarization-induced spreading depression is the pathophysiological correlate of the migraine aura and a review of the spreading depolarization continuum of acute neuronal mass injury

Spreading depolarization is observed as a large negative shift of the direct current potential, swelling of neuronal somas, and dendritic beading in the brain’s gray matter and represents a state of a potentially reversible mass injury. Its hallmark is the abrupt, massive ion translocation between i...

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Bibliographische Detailangaben
Veröffentlicht in:GeroScience
Hauptverfasser: Major, Sebastian, Huo, Shufan, Lemale, Coline L., Siebert, Eberhard, Milakara, Denny, Woitzik, Johannes, Gertz, Karen, Dreier, Jens P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer International Publishing 2019
Schlagworte:
Review
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7031471/
https://ncbi.nlm.nih.gov/pubmed/31820363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-019-00142-7
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