REEP5 depletion causes sarco-endoplasmic reticulum vacuolization and cardiac functional defects

The sarco-endoplasmic reticulum (SR/ER) plays an important role in the development and progression of many heart diseases. However, many aspects of its structural organization remain largely unknown, particularly in cells with a highly differentiated SR/ER network. Here, we report a cardiac enriched...

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Vydáno v:Nat Commun
Hlavní autoři: Lee, Shin-Haw, Hadipour-Lakmehsari, Sina, Murthy, Harsha R., Gibb, Natalie, Miyake, Tetsuaki, Teng, Allen C. T., Cosme, Jake, Yu, Jessica C., Moon, Mark, Lim, SangHyun, Wong, Victoria, Liu, Peter, Billia, Filio, Fernandez-Gonzalez, Rodrigo, Stagljar, Igor, Sharma, Parveen, Kislinger, Thomas, Scott, Ian C., Gramolini, Anthony O.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7031342/
https://ncbi.nlm.nih.gov/pubmed/32075961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-14143-9
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