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NF-κB c-Rel Dictates the Inflammatory Threshold by Acting as a Transcriptional Repressor
NF-κB/Rel family of transcription factors plays a central role in initiation and resolution of inflammatory responses. Here, we identified a function of the NF-κB subunit c-Rel as a transcriptional repressor of inflammatory genes. Genetic deletion of c-Rel substantially potentiates the expression of...
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| Publicado no: | iScience |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7031323/ https://ncbi.nlm.nih.gov/pubmed/32062419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.100876 |
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