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Controllability analysis of molecular pathways points to proteins that control the entire interaction network

Inputs to molecular pathways that are the backbone of cellular activity drive the cell to certain outcomes and phenotypes. Here, we investigated proteins that topologically controlled different human pathways represented as independent molecular interaction networks, suggesting that a minority of pr...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Devkota, Prajwal, Wuchty, Stefan
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7031241/
https://ncbi.nlm.nih.gov/pubmed/32076007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-59717-6
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