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Controllability analysis of molecular pathways points to proteins that control the entire interaction network

Inputs to molecular pathways that are the backbone of cellular activity drive the cell to certain outcomes and phenotypes. Here, we investigated proteins that topologically controlled different human pathways represented as independent molecular interaction networks, suggesting that a minority of pr...

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Pubblicato in:Sci Rep
Autori principali: Devkota, Prajwal, Wuchty, Stefan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7031241/
https://ncbi.nlm.nih.gov/pubmed/32076007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-59717-6
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