The transfer of specific mitochondrial lipids and proteins to lipid droplets contributes to proteostasis upon stress and aging in the eukaryotic model system Saccharomyces cerevisiae

Originally Lipid droplets (LDs) were considered as being droplets for lipid storage only. Increasing evidence, however, demonstrates that LDs fulfill a pleiotropy of additional functions. Among them is the modulation of protein as well as lipid homeostasis. Under unfavorable pro-oxidative conditions...

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Gepubliceerd in:GeroScience
Hoofdauteurs: Geltinger, Florian, Tevini, Julia, Briza, Peter, Geiser, Amrito, Bischof, Johannes, Richter, Klaus, Felder, Thomas, Rinnerthaler, Mark
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer International Publishing 2019
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7031196/
https://ncbi.nlm.nih.gov/pubmed/31676965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-019-00103-0
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