circRNAs expressed in human peripheral blood are associated with human aging phenotypes, cellular senescence and mouse lifespan

Circular RNAs (circRNAs) are an emerging class of non-coding RNA molecules that are thought to regulate gene expression and human disease. Despite the observation that circRNAs are known to accumulate in older organisms and have been reported in cellular senescence, their role in aging remains relat...

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Udgivet i:GeroScience
Main Authors: Haque, Shahnaz, Ames, Ryan M., Moore, Karen, Pilling, Luke C., Peters, Luanne L., Bandinelli, Stefania, Ferrucci, Luigi, Harries, Lorna W.
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2019
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7031184/
https://ncbi.nlm.nih.gov/pubmed/31811527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-019-00120-z
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