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Characterizing the Dysfunctional NK Cell: Assessing the Clinical Relevance of Exhaustion, Anergy, and Senescence

There is a growing body of literature demonstrating the importance of T cell exhaustion in regulating and shaping immune responses to pathogens and cancer. Simultaneously, the parallel development of therapeutic antibodies targeting inhibitory molecules associated with immune exhaustion (such as PD-...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Judge, Sean J., Murphy, William J., Canter, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7031155/
https://ncbi.nlm.nih.gov/pubmed/32117816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2020.00049
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