LXRs regulate features of age-related macular degeneration and may be a potential therapeutic target

Effective treatments and animal models for the most prevalent neurodegenerative form of blindness in elderly people, called age-related macular degeneration (AMD), are lacking. Genome-wide association studies have identified lipid metabolism and inflammation as AMD-associated pathogenic pathways. Gi...

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Publicado en:JCI Insight
Autores principales: Choudhary, Mayur, Ismail, Ebraheim N., Yao, Pei-Li, Tayyari, Faryan, Radu, Roxana A., Nusinowitz, Steven, Boulton, Michael E., Apte, Rajendra S., Ruberti, Jeffrey W., Handa, James T., Tontonoz, Peter, Malek, Goldis
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2020
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7030875/
https://ncbi.nlm.nih.gov/pubmed/31829999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.131928
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