Nrf2 activation protects against lithium-induced nephrogenic diabetes insipidus

Lithium (Li) is the mainstay pharmacotherapeutic mood stabilizer in bipolar disorder. Its efficacious use is complicated by acute and chronic renal side effects, including nephrogenic diabetes insipidus (NDI) and progression to chronic kidney disease (CKD). The nuclear factor erythroid-derived 2–rel...

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Bibliographic Details
Published in:JCI Insight
Main Authors: Jobbagy, Soma, Vitturi, Dario A., Salvatore, Sonia R., Pires, Maria F., Rowart, Pascal, Emlet, David R., Ross, Mark, Hahn, Scott, St. Croix, Claudette, Wendell, Stacy G., Subramanya, Arohan R., Straub, Adam C., Tan, Roderick J., Schopfer, Francisco J.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2020
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7030822/
https://ncbi.nlm.nih.gov/pubmed/31941842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.128578
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