Immunologic alterations in the pancreatic cancer microenvironment of patients treated with neoadjuvant chemotherapy and radiotherapy

Pancreatic ductal adenocarcinoma (PDAC) has dismal 5-year survival (<9%). We hypothesize that exposure of tumors to conventional therapies may preferentially modulate immune biomarkers in the tumor microenvironment in PDAC. PDAC patients who underwent upfront surgical resection or who received ne...

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發表在:JCI Insight
Main Authors: Farren, Matthew R., Sayegh, Layal, Ware, Michael Brandon, Chen, Hsiao-Rong, Gong, Jingjing, Liang, Yan, Krasinskas, Alyssa, Maithel, Shishir K., Zaidi, Mohammad, Sarmiento, Juan M., Kooby, David, Patel, Pretesh, El-Rayes, Bassel, Shaib, Walid, Lesinski, Gregory B.
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2020
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7030821/
https://ncbi.nlm.nih.gov/pubmed/31830001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.130362
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